Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation
Enzo Berardesca, MD,1 Norma Cameli, MD,1Claudia Cavallotti, MD,1Jean Luc Levy
, MD,2Gerald E Pierard, MD,3& Gianfranco de Paoli Ambrosi, PhD 4
1San Gallicano Dermatological Institute, Rome, Italy
2Center Laser, Marseille, France
3Department of Dermatology, University Hospital of Liege, Liege, Belgium
4General Topics, Worldwide Health Care Products, San Felice d/B, Italy
Results: A statistically significant improvement was observed in many clinical and instrumental parameters investigated (P <0.001). In particular, improvement of skin redness, papules, itching, hydration, and skin color occurred. The combination of silymarin and S-MSM can be useful in managing symptoms and condition of rosacea skin, especially in the rosacea subtype 1 erythemato-telangiectatic phase. The action can be considered multicentric and multiphase because of the direct modulating action on cytokines and angiokines normally involved and up-regulated in the case of such skin condition. Publication or presentation: 2008 Blackwell Publishing •Journal of Cosmetic Dermatology,7, 8–14 Product :Synchrorose FAST蒙娜麗莎加強型修護乳霜
2007 Study: 怯痘產品對修護痤瘡的效果和耐受性。
Double-blind, randomized, placebo-control study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris
Charakida, M. Charakida and A. C. Chu
Department of Dermatology, Hammersmith Hospital, Ducane Road, London W12 0NN, U.K Results: Forty patients were recruited into the study, of whom 33 completed the study. Active treatment was statistically superior to placebo in reduction of Leeds grading and total, inflammatory and noninflammatory lesion counts. The active lotion showed a rapid response with obvious reduction in lesion counts and acne
grading by 4 weeks. Sebum production was significantly reduced in the actively treated group, with a mean reduction of 53% in sebum production compared with baseline. One patient developed irritation to the active lotion and withdrew from the study. Publication or presentation: THERAPEUTICS DOI 10.1111/j.1365-2133.2007.08083.x Product :AKNICARE Lotion袪痘擦劑
2007 Study: 潤白產品對修護黑斑有有效性和刺激評估
Skin-Lightening Formulation: A Comparative In Vivo and In Vitro Study
Stefania Briganti, PhD; Norma Cameli, MD; Mauro Picardo, MD Results: Our in vitro and in vivo data confirm that the linoleic acid- combination is able to inhibit melanin production. From our clinical results, we conclude that the combination could be proposed as an effective, safe treatment for melasma. Publication or presentation: Cosmetic Dermatology.April 2007.VOL 20 No.4 Product :
Thiospot Intensive Cream蒙娜麗莎潤白精華霜
2007 Study: 硫辛酸對抗老化的功效針對蒙娜麗莎產品
Antioxidants and narrowband-UVB in the treatment of vitiligo: a double-blind placebo controlled trial
Whitening Effect of a Dermocosmetic Formulation: a Randomized Double-Blind Controlled Study on melasma
L. Thirion.C. Pierard-Franchimont and G.E. Pierard
Department of Dermatopathology, University Hospital Start Tilman, Liege, Gelgium. Result or conclusion of study : A significant lightening effect was evidenced beginning the second month of treatment with the whitening formulation. Publication or presentation:International Journal of Cosmetic Science, 2006, 28, 263-267 Product :Thiospot Intensive Cream蒙娜麗莎潤白精華霜
2006 Study: 評估50% 焦葡萄酸換膚劑對於光害、表層疤、肝斑皮膚修護是否有效。
Clinical and Instrumental Evaluation of Skin Improvement after Treatment with New 50% Pyruvic Acid Peel
Enzo Berardesca, MD, Norma Cameli, MD, Garazia Primavera, MD, And Manuela Carrera, MD* Result or conclusion of study : This innovative formulation of 50% pyruvic acid peel has been shown to be safe and effective to treat photodamage, melasma, and superficial scarring, allowing
the patients to carry out regularly their working life as well as their social life. Publication or presentation: 2006 by the American Society for Dermatologic Surgery, Inc. Product : Enerpeel PA 蒙娜麗莎焦葡萄酸換膚
2002 Study:水飛薊對酒糟性肌膚的修護
Open Evaluation of Silymarin Cream in the Management of Facial Redness Associated With Rosacea
Gai L. Nield, md, FRCPC; Richard Ippersiel, BSc Result or conclusion of study : Topical silymarin-containing cream is a safe and effective product for reducing facial redness associated with rosacea and can be used effectively with common topical medications for the treatment of rosacea. Publication or presentation:Vol. 15 No. 8 August 2002, Cosmetic Dermatology 15 Product : Synchrorose Intensive Cream 蒙娜麗莎舒敏乳霜
1998 Study: 彈膚麗臉霜對雷射手術後的修護
Erythema after Aesthetic Laser surgery A solution for this problem with a new treatment concept
SPILKER, G., KUPPERS, S., TOLKDORF, A., HILPERT, A. Result or conclusion of study : In this study we could demonstrate that it is possible to reduce some of the most annoying side effects pain, tension and especially the postoperative erythema, by including Terproline cream in the post-operative open wound management. Publication or presentation:ATHENS,HELLAS 5-7 FEBRUARY 1998 .European Society for Laser Aesthetic Surgery Product :Terproline Face Cream 蒙娜麗莎彈膚麗臉霜
1997 Study: 彈膚麗對損傷和老化、燒燙傷,外傷肌膚的修護
Dermofunctional treatment of hypertrophic burn scars
De Santis P., Savoia A.Department of Plastic Surgery and Burn Unit, Brindisi, Italy Result or conclusion of study : The results indicate that hypertrophic scars in the Sychroline group were more elastic and pliable at six months than those in the hydrating cream group. The effect of Terproline as a precursor and stimulator of hyaluronic acid, fibronectin and soluble collagen biosynthesis is discussed. Publication or presentation:Annals of Burns and Fire Disasters - vol. X - n. 3 – September 1997 Product :Terproline Body Cream蒙娜麗莎彈膚麗體霜